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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NPHS1
All Species:
19.09
Human Site:
T416
Identified Species:
46.67
UniProt:
O60500
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60500
NP_004637.1
1241
134742
T416
E
D
N
G
L
T
L
T
C
E
A
F
S
E
A
Chimpanzee
Pan troglodytes
XP_524228
1241
134508
T416
E
D
N
G
L
T
L
T
C
E
A
F
S
E
A
Rhesus Macaque
Macaca mulatta
XP_001112314
1052
113512
Q283
L
Q
W
L
K
N
G
Q
P
V
S
T
A
W
G
Dog
Lupus familis
XP_541685
1242
135134
T416
E
D
N
G
L
T
L
T
C
E
A
F
S
E
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9QZS7
1242
134872
T416
E
D
N
G
L
S
L
T
C
E
A
F
S
D
A
Rat
Rattus norvegicus
Q9R044
1234
134286
T412
E
D
N
G
L
P
L
T
C
E
A
F
S
D
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001035777
1242
137333
Q407
E
D
N
G
L
S
L
Q
C
E
A
F
N
K
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q08180
764
82987
Honey Bee
Apis mellifera
XP_624127
1307
143527
I476
A
S
D
N
N
A
R
I
R
C
E
A
A
N
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796903
1010
110769
T241
Q
G
I
L
S
T
S
T
L
R
L
I
L
D
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
80.9
87
N.A.
82.5
81.8
N.A.
N.A.
N.A.
N.A.
38.8
N.A.
20.9
26.9
N.A.
21.1
Protein Similarity:
100
99.5
83
92.6
N.A.
89.6
89.3
N.A.
N.A.
N.A.
N.A.
54.8
N.A.
33.6
42.9
N.A.
35.9
P-Site Identity:
100
100
0
100
N.A.
86.6
86.6
N.A.
N.A.
N.A.
N.A.
66.6
N.A.
0
0
N.A.
13.3
P-Site Similarity:
100
100
13.3
100
N.A.
100
93.3
N.A.
N.A.
N.A.
N.A.
86.6
N.A.
0
20
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
10
0
0
0
0
60
10
20
0
50
% A
% Cys:
0
0
0
0
0
0
0
0
60
10
0
0
0
0
0
% C
% Asp:
0
60
10
0
0
0
0
0
0
0
0
0
0
30
0
% D
% Glu:
60
0
0
0
0
0
0
0
0
60
10
0
0
30
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
60
0
0
0
% F
% Gly:
0
10
0
60
0
0
10
0
0
0
0
0
0
0
20
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
0
0
0
0
10
0
0
0
10
0
0
0
% I
% Lys:
0
0
0
0
10
0
0
0
0
0
0
0
0
10
0
% K
% Leu:
10
0
0
20
60
0
60
0
10
0
10
0
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
60
10
10
10
0
0
0
0
0
0
10
10
0
% N
% Pro:
0
0
0
0
0
10
0
0
10
0
0
0
0
0
0
% P
% Gln:
10
10
0
0
0
0
0
20
0
0
0
0
0
0
10
% Q
% Arg:
0
0
0
0
0
0
10
0
10
10
0
0
0
0
0
% R
% Ser:
0
10
0
0
10
20
10
0
0
0
10
0
50
0
10
% S
% Thr:
0
0
0
0
0
40
0
60
0
0
0
10
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% V
% Trp:
0
0
10
0
0
0
0
0
0
0
0
0
0
10
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _